Clinical Trials by Specialty

EPILEPSY

Lundbeck: A prospective, open-label study of the structure and function of the retina in adult patients with refractory complex partial seizures treated with vigabatrin (Sabril®). For more information contact Mary 309-624-8401.

SP902: A historical-controlled, multicenter, double-blind, randomized trial to assess the efficacy and safety of conversion to Lacosamide 400mg/day Monotherapy in subjects with partial-onset seizures. For more information contact Mary 309-624-8401.

SP904: A multicenter, open-label extension trial to assess the long-term use of Lacosamide Monotherapy and adjunctive therapy in subjects with partial-onset seizures. Subjects must have completed the SP902 study. For more information contact Mary 309-624-8401.

UCB 1358: A randomized, double-blind, placebo-controlled, multicenter, parallel-group study to evaluate the efficacy and safety of brivaracetam in subjects with partial onset seizures. For more information contact Mary 309-624-8401.

UCB 1379: An open-label, multicenter, follow-up study to evaluate the long-term safety and efficacy of brivaracetam used as adjunctive treatment in subjects with partial onset seizures. Subjects must have completed the 1358 study. For more information contact Mary 309-624-8401.

V-Compas: A post-market, long term, prospective, observational, multi-site outcome study to follow the clinical course and seizure reduction of patients with refractory seizures who are being treated with adjunctive VNS (vagus nerve stimulation) therapy. For more information, contact Sarah at 309 655-7837.

MULTIPLE SCLEROSIS

ASCEND: A study to evaluate the efficacy of Tysabri in reducing disability progression in patients with Secondary Progressive Multiple Sclerosis (SPMS). For more information contact Kim C. at 309-655-7397.

Stratify 2: Study to check presence of JCV antibody in patients with Relapsing Multiple Sclerosis receiving or considering treatment with Tysabri. For more information contact Kim C. at 309-655-7397.

NEUROSURGERY

A prospective study of the relationship of neuropsychological and motor performance parameters with magnetic resonance imaging in athletes with mild traumatic brain injury. For more information contact Sarah at 309-655-7837.

Exogen: A Prospective, Multi-center, Double-blind, Randomized, Placebo Controlled Pivotal Study of Ultrasound Therapy as Adjunctive Therapy for Increasing Posterolateral Fusion Success Following Single Level Posterior Instrumented Lumbar Surgery (All enrolled patients will have undergone single level lumbar fusion).  For more information contact Sarah at 309-655-7837.

HSRT: A Pilot Study Examining the Role of Pre-Operative Hypofractionated Stereotactic Radiation Therapy followed by Surgery in the Treatment of Cerebral Metastatic Disease.  For more information, contact Sarah 309 655-7837.

Licox: A Pilot Study Examining the Role of Brain Tissue Oxygen Monitoring in the Detection of Cerebral Vasospasm Secondary to High Grade Aneurysmal Subarachnoid Hemorrhage.  Inpatient study.  For more information, contact Sarah at 309 655-7837.

Use of Neuroimaging to Study the Pain Network in Patients of Trigeminal Neuralgia. For more information, contact Sarah at 309 655-7837.

STROKE

Iris: A study to test the effectiveness of a new treatment (pioglitazone) for preventing future strokes and heart attacks among persons with a recent stroke or TIA.  For more information contact Judi at 309-624-3240.

Respect PFO: A study for patients with Stroke and Patent Foramen Ovale (PFO), comparing an investigational PFO occluder device, to current standard of care treatment in preventing another stroke. For more information contact Judi at 309-624-3240.

For information regarding other clinical trials in the area please visit the following links.

Peoria Radiology Research and Education Foundation
Central Illinois Radiology Associates
http://peoria.medicine.uic.edu/departments___programs/radiology/research/

Illinois Cancer Care
http://www.illinoiscancercare.com/index.cfm?pageID=6

Illinois Lung Institute
Peoria Pulmonary Associates, Ltd.
http://www.illinoislunginstitute.com/research.shtml

OSF Medical Group-Clinical Research Center
http://www.osfmedicalgroup.org/research.html

Radiation Therapy Oncology Group's (RTOG) Brain Tumor Research Trials

Saint Jude-Midwest Affiliate
http://www.stjuderesearch.org/

Children's Hospital of Illinois
http://www.childrenshospitalofil.org/default.htm

University of Illinois College of Medicine at Peoria
http://peoria.medicine.uic.edu/research